Wednesday, February 25, 2015

Enamel birefringence: Research Topic in Frontiers - Frontiers in Physics (Biomedical Optics): call for papers

     The Frontiers Research Topic in Physics (Biomedical Optics) on Enamel birefringence is now open for submissions of contributions. 
Frontiers Research Topic on Enamel Birefringence

     Enamel birefringence had its importance in the dental scientific literature boosted by two articles published in Nature in the 60's (Poole et al. , Nature 189: 998, 1961, doi: 10.1038/189998a0; Silverstone, Nature 214:203-204, 1967, doi:10.1038/214203a0). The main contributions came from scientists working at the University of Bristol (UK) led by Dr. AI Darling. Those papers presented enamel as a molecular sieve and the "relatively intact" surface zone of enamel caries. The early data on the quantification of the volume of materials infiltrated into enamel pores and on the distribution of different pore sizes in enamel caries had a highly influential impact in dental research, particularly in the idea of the carious process as a de- and remineralization process. 
    Enamel features under polarizing microscopy became so popular that its use in scientific papers started not to be accompanied by citations to the papers from the group of Bristol, as if it had become a basic knowledge of general pubic domain by the scientific literature. Despite the papers in Nature present a low number of citations in Google Scholar, a search for "dental enamel and polarizing microscopy" in Google Scholar returns with 12,400 results (as of February 24 2015), not to mention other combinations of keywords related to enamel birefringence. Nearly all those results are related to works by AI Darling, which have been confronted with new and conflicting results. New developments in optical birefringence under light microscopy opened new avenues to explore the features of dental enamel under polarizing microscopy, including the study of transport of materials in real time and with spatial resolution. Enamel birefringence is in the heart of dental caries, the most prevalent chronic disease in humans worldwide, and dental caries, in turn, is in the heart of Dentistry. There are also applications of enamel birefringence to tooth whitening, fluorosis, amelogenesis, and resin-enamel hybrid layer. A reappraisal with new evidences can bring novel ideas to improve oral health.

0 Comments:

Post a Comment

<< Home